This lecture in the Chemical Biology series is proving to be something special. Together with the IBL and LACDR we have invited Derek Lowe. Dr. Lowe is not only the director of Chemical Biology Therapeutics of Novartis. He is also the writer of the widely read ‘in the pipeline’-blog in which he casts an insightful eye on the pharmaceutical industry. His talk titled ‘The Problem with Drug Discovery’ will thus provide an exciting interesting insider’s view on the workings of this industry.